Jacques-Louis Potgieter has replaced Patrick Lambie in the Sharks team to face the Crusaders at Twickenham on Sunday.
The Sharks have added Eugene van Staden and Gerhard Mostert to their touring squad headed to London while JP Pietersen has also passed a fitness test and will fly out together with the team.
The Sharks are taking just 22 players to London with no back up players as they feel they can fly out an emergency replacement quickly if needed.
John Smit will again captain an almost unchanged side for possibly their toughest clash of the season and the only change is that of Potgieter replacing Lambie while Eugene van Staden adds front row depth off the bench with Craig Burden and Anton Bresler remaining behind.
Gerhard Mostert is named amongst the reserves along with fit-again JP Pietersen.
Looking ahead to the game, captain John Smit is enthusiastic at the prospect of this history-making event. "I hope we get a good crowd for this match because there are hundreds of thousands South African and New Zealand ex-pats living in the UK.
"Hopefully we'll see more Black and White than Black and Red in the crowd." he said on the
Sharks site.
"There has been a huge amount of excitement about this game and people over there are hungry for Super Rugby and this is a wonderful opportunity for them to be able to support their teams in real life.
" I'm pretty sure it will be well-supported, not only because there are two good Super Rugby teams playing each other, but because it's for a good cause."
The Sharks
1. John Smit (Capt) , 2. Bismarck du Plessis , 3. Jannie du Plessis , 4. Steven Sykes , 5. Alistair Hargreaves , 6. Keegan Daniel , 7. Willem Alberts , 8. Ryan Kankowski , 9. Charl McLeod , 10. Jacques-Louis Potgieter , 11. Lwazi Mvovo , 12. Meyer Bosman , 13. Stefan Terblanche , 14. Odwa Ndungane , 15. Louis Ludik
Replacements , 16. Eugene van Staden , 17. Tendai Mtawarira , 18. Gerhard Mostert , 19. Jacques Botes , 20. Conrad Hoffmann , 21. Adrian Jacobs , 22. JP Pietersen